Methanol 99.8% HPLC Grade

A high-purity form of methanol that is specifically manufactured and purified for use in high-performance liquid chromatography (HPLC) and other analytical techniques. In HPLC, the choice of solvent is critical because any impurities in the solvent can interfere with the separation and detection of compounds in the sample. Impurities can lead to baseline noise, inaccurate peak detection, and altered retention times. Therefore, using solvents of high analytical grade, such as Methanol 99% HPLC Grade, helps ensure that the analytical results are reliable and consistent.

Methanol 99.8% HPLC Grade is a liquid solvent manufactured and purified for high performance liquid chromatography and other analytical work. Its CAS number is 67-56-1, and it’s sold as HPLC grade. That grade matters because impurities in a solvent can cause baseline noise, throw off peak detection and shift retention times. A cleaner solvent helps your results stay reliable and consistent from one run to the next. You won’t have to chase paperwork either. The Product Manuals section lists the Safety Data Sheet, the Technical Data Sheet and a long run of Certificates of Analysis. It also includes statements on allergens, BPA, conflict materials, gluten free, GMO free, heavy metals, nitrosamines, PFAS and PFOS free, source, and TSE/BSE.

Most people reach for this methanol when they run HPLC analysis, prepare samples and calibration standards, or extract compounds from solid samples. It also works as a solvent for spectroscopy sample prep and for reagents. The problem? A solvent that isn’t clean enough, or missing paperwork, can stall your work. Sizes run from 1 gallon and 4 liter containers up to 55 gallon drums, and we handle hazmat shipping from start to finish. Here’s the simple plan. Choose your size, set up Autoship if you reorder often, or ask for a quote on larger volumes. You’ll get it on budget, on time, every time. Ready to go? Request a quote and we’ll take it from there.

Common Uses and Applications

HPLC analysis and compound separation

Sample preparation and dilution

Solvent for spectroscopy sample preparation

Calibration standard preparation

Solvent for liquid chromatography mass spectrometry

Solvent for laboratory reagents

Extracting compounds from solid samples

Cleaning and degreasing lab equipment

Q: What is Methanol 99.8% HPLC Grade used for? A: It’s used as a solvent in HPLC analysis, sample and standard preparation, spectroscopy sample prep and LC/MS work. Labs also use it to dissolve reagents, extract compounds from solid samples, and clean and degrease equipment.

Q: What does HPLC grade mean, and is it suitable for HPLC analysis? A: HPLC grade means the methanol is manufactured and purified specifically for high performance liquid chromatography. Impurities in a solvent can cause baseline noise, inaccurate peak detection and shifted retention times, so this grade is made for that kind of work.

Q: What sizes are available, and does it ship as hazmat? A: You can choose 1 gallon, 4 liter, 55 gallon, a case of four 1 gallon units or a case of four 4 liter units. Yes, it ships as hazmat and requires a hazmat fee. The DOT line on the page reads: DOT: Methanol, 3, UN1230, PG II.

Q: How do I get the SDS and Certificate of Analysis? A: Open the Product Manuals section on this page. The Safety Data Sheet and Technical Data Sheet are listed there, and the Certificates of Analysis sit in their own tab, listed by lot number.

Q: How should it be stored? A: Check Section 7 of the Safety Data Sheet for handling and storage guidance, since it’s written for this exact product. Our storage blog post isn’t listed on this page, so there’s no link to add yet.

Q: Which statements and documents come with this product? A: Besides the SDS, TDS and Certificates of Analysis, the Product Manuals list statements on allergens, BPA, conflict materials, gluten free, GMO free, heavy metals, nitrosamines, PFAS and PFOS free, source, and TSE/BSE.

Q: Can I set this up on Autoship? A: Yes. The page shows Autoship as available, so you can have it delivered on a schedule you choose.

Q: Can I order larger volumes? A: The 55 gallon size is listed on the page. If you need more, request a quote and we’ll work out the details with you.

Competitive pricing and well-stocked US-based inventory.

Fast 1-2 business days shipping, including hazmat transport.

Exceptional customer service and chemical technical support.

Delivery on budget, on time, every time.